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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f39a021f3736c3f7de75a0fe5e4dfefd64f53249a579149b2be2537690740fd' 
  AND token = 'kAAwrZFAGuvwlU1QnHTrrVU8a0Jf6C0CJM8Bik8nkdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}