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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9288d132fa91dd099965aa4a628763bc7a1b6a9c1be34da79e013a1da445831d' 
  AND token = 'sN8CQ/Tt1+fWPmbxAJeJp6mxqqxZXAo+X+v2ZrP68C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}