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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9e6e1a378402d302eaca02ebd5aad8adae5c0fc12eb04a4d4a85677422f090' 
  AND token = 'x8ZeLyPmZXvum8NsTpcWhj4vtN9rijIBczXZLSeg4Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}