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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859d09bcd7faa890dd5088a041194e9e763224da89c2e9cd8672423a2e39aa8d' 
  AND token = 'Taua4R96NwkRM4L0IXYGum7qrhoS/doZ5O1WKIZ5ong=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}