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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fe105f4c401c283d8ce8b583fbfb8933288a7b5ea2498081d455952c246a446' 
  AND token = '8o0l6C91pURig1x3TY11Q/Moan+L0cnpDh+SLj5wSjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}