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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31f9fca5a813a918fe649bc7043ac1f4f4b651c4ca57a144013670d74cbed180' 
  AND token = 'ceFyR4cH2aEbaESPnxnhxeaKfAzUwHb/gN+KaohPm6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}