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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93fdb43f3183298a92b11c9289116ca3fd416100ecb2a42a994e73604386364f' 
  AND token = 'Am2FAguUKOKkI3+Ak4p21CZaUHGl+Tx3zxr1Rhs1094=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}