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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd345a798a5e6e235fe79cd50f5e4b60a4933ac701dd36f8eabcc18aaea4e5606' 
  AND token = 'E6OdKxbuvnfqpzvTUBgPezTXu6El6BoknCmp4AmnWZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}