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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b4efe80d5672f27dcda98a408be982d4b06cf4027364a584f00f287d34c66ff' 
  AND token = 'MrRM9vp4a2teibZyqjMnsOQzuxvf/32GlqCaR7EJm50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}