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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a571451d7137039ce8e5f814c8481b28203149310285561a586aab920d74f24' 
  AND token = 'sfmi20vH33iq47rZHGMbcRtT/7n5ISs3YLPKIWA49WQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}