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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d46865dbfa7b436b2a8330276ec79b43a6fa1dc7823fda3ed8fdb1b18349afd' 
  AND token = '+WzluvJ2qiKk880xJURO3AFtuufAaK8U+3gzt/ldMuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}