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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2580feb8eed0ce403f1b8ccd2a3dbc5fc43809511d7921041ac9e5fb3b2469fe' 
  AND token = 'ZztHH4aAIXa/tHWfWbV+nXm7Ntzx8e91G1irgZ2bE4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}