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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f66cdb3be07e750759fede072ebd580cf6533d014ffb3982f2d8f6970c6d537' 
  AND token = '4Ea2dLgtk26lR575ALRI+4TroHarsEdzLqwH/rdwl0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}