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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d818f165e30cee4fb839a275fd436431966e3b6c8fa1a759ac640f4021d0cfb' 
  AND token = 'YQaaNUcg0OhJw+CAzxgh9NQRwRSy3FaWig1+QvTOJd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}