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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c397e7981975ab3d2caec4745b6e5b29f2801955a81c870a504a23a22cbac4ca' 
  AND token = 'tk/oMf10iaM8swYJtIGiuHA+UOeqfEVbYI4fsX9Zx+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}