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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300cb703d3f8658ec65a3b9440a0adff821862ef6e6fc91134e803e1349ea555' 
  AND token = '7fpK6dj41t7137g+dkZksOjvstBNew8uJBzDemhtq1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}