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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdd44c6f2b640a937fb7a4fe6f771e4ff6689a5be7ad8d273a910a1f6b02c275' 
  AND token = 'x4LcsNaEG5z/K7hMb2jeoyh6Ae+usU3mrXm88JhAVAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}