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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cd2ebf48a15c5de31d1efc3ca7e5f8ca4a046b96b1cc0529671d2b457a34d6' 
  AND token = 'OYN3mIlS7F4KtY7D/+fXIkeKGJqdNeYtN2tOpcld138=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}