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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34cfeff40d1f654d5d6ff286768830780a018feb72af908d214276c4d586950e' 
  AND token = 'uFim3sh9btYp1xzEfqg+2H7mv9ud8dNUCgN1E2KW7nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}