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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f49aefefd352685bee152d425641a5f24c2a2c67bd1030ee568ca6cbd83726' 
  AND token = 'i1mCNaU4l2Gjl7IC/UuOSRhnYmOOYBq24jOqUz5pVAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}