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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08b7e4acc3b3c29c96508243760930ba00c625b97b8d3a749be10056f8b118c4' 
  AND token = 'm8wZE/3aT0B3cRO6gQ339+SZBvj/ehbNxH5xEpxMcI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}