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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2d8307ee46fcacfff52162da3683410ee8374a26d5fc641f01b7288ac9ac71' 
  AND token = 'TP/DU8WfVQjleAO4bzgINTqDSgpH88UlnB+NJVu/37A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}