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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837215caa22703e5c6207909c029c857fd2fbd45f1f078f32c307c1ee3aa304d' 
  AND token = 'E/Ve4WCMSYH2r6X8sk9YymPi/dfAmM4KnZ7FsfB/cxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}