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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5da47377c8a183561f7838b141341435afad729cba4475c858227e304deae48' 
  AND token = 'TiQRr1S+INDi1sxvUDYaK1Cp1bxwcMgJVd7JH3WHj2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}