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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bdfec00d86031ad91a09e8ede9c0cafb6e44916d6ba5c89fb6b2173ff3ee372' 
  AND token = 'pdA4UMl2Z18ACBx/GqGb6OQ0ZpbPUouSzeXakESt3OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}