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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6c18679621763aec9e286aa2a5b28d436b57b71219520a7bc8639e6a22bce6' 
  AND token = 'HYk7p7crQlNaM+KPuPQsc7kg6umoyUXzOss0fLKrcjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}