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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3c018b72d5b4ac07e6d3fc1f2984bb79dc18812e099902130034d18dc1b756' 
  AND token = 'w323jcAV31AlMwyEV7rGi2HzLBFqaUn6hQsZmhuc3hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}