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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '242128526400d64bc16ffe022735e838cb0e348f1c22cb6b5eaa362dd4d4b418' 
  AND token = 'M1PDA8QZAPt2MX08/sjQNiNfV0UGo5/0uDHuLz/QBQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}