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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50aa25825a88d35d95a67c61d6868ea216565ca2208defa2ccb8d779d97e0a7' 
  AND token = 'hvMDmp2d/9IZYm2sEdDpa9UIwoCVyXzi9qIY7/6iBuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}