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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6aba656cfef27b53863da8f59f374402275b29387360e9df0035f59d3ee0dd6' 
  AND token = 'EqdY3iEdZ/VHh6wbf21iHHjQfKukjBbYsyTe//3rrUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}