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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45eb685453ba8385549b78efe781a70200391772a6a3869f328fd6c7865ee7b' 
  AND token = 'j2FmlmQrpDCQ2n20Dj8WxLDeRIuli+16XbHqfC1LXVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}