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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a0d5f84df079d2ced3ea384f70e861408742f8c105f2fc4e8881621667ed3e' 
  AND token = 'VSsaVBKr1289Vj9+TFccCPiKm7sKEUtfQuzn+6SC0gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}