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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0b141b7d81fe9068616d78416d4d6861ebbc09e4f68394f61ccfe4b3dda5c44' 
  AND token = 'RMIa/UHB0OABNmG+IXTBVKftHr1D8jIf0M+pFyV8nzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}