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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb17063735019592544edc756d8b10b95bdc6481d6704f70dabc1b01a652a41' 
  AND token = '6pkTSTyiZtOazws9Yxwe1BQ9/4j+8oEi9Y3TbecbBYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}