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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13ed1b4518e8a4008a9c781695da3dd00b662ccd2c377fb8ff9e811a3df78206' 
  AND token = 'JdI9iPTNJCVI03X+nLMiRBsxNER+zxET8PQnOHDl1sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}