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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228de0e07d7a81fda44a5b6c515cdecca6a9b694511dda2da601d73365a97978' 
  AND token = 'uBV4SypaDgzdcFnmeurE00yJF5grPv9cihxL1A+1JLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}