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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7a201c228af3026831228cb629a66fc6e64fb23b8aaf286b57499e2abf8d7b' 
  AND token = 'NLJj52u6keMyWMu0puoyzI87VmyUS6CU18uoVeweU5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}