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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d08590318b7d20a150c9327e1d6f60342e4f33d1e6910db438dccdf734c2caa' 
  AND token = '22pwVgxWrpGmiQrmQgjjqwzL7j/j8Lrd0zbCwVvA/R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}