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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328ddff96c74846448a5d8bdb49df207e20d4fdd4b5665b87edcd53d15bca5ee' 
  AND token = 'm2C49FrLlQR6NYSPMkh6SZR7RIBUUGhmUPAZ2bul6xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}