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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97931a55debd11aa8470a37b4bdd343723e81dc7e4da1a30eebb02356236a29f' 
  AND token = 'duO4kD6wxUv7NLTg8tbilI3w+sIH9WVM16zsFyvslAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}