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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5e0f7eeb4c2b07ef6959c0f2c28b7be0388c6fd1b04a49dd263cee0e520861' 
  AND token = 'RJse3Dm9+YxskV2PLXTV19C0UNat+HaD3dJbXZH1PF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}