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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54c4fee56be9dbc612964c44b42ddb24896001962556e8922d9862acb1ea5fc8' 
  AND token = '6ymx5MYklyaf5C64jdCy4+cwkGgAuCAWJCUKNZiHC/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}