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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18b80f1dd0bebe4c371d0800be86cecafbaa6a1e81288548149c0851327494e' 
  AND token = 'sv7foSm8px3vxT5gWpJd1d54JjtlAxJNB1QZ8EpYXNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}