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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6443fe7f959e55caab50b0c50240432537a2d8c4c3dd2c4f00b698b3c4f5a985' 
  AND token = '4FGedFBefffKLFgzcL6Xm6xsDOVRAWdfqJYpEHxgk+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}