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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0421b405142b669c2f6e9642ef589134e73945a75d20cf822da4cc0f66a7c4e' 
  AND token = '0xtnHfMJcAmLVNKeFgIr7gmxMi1xfMVhka4GZJIheQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}