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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7575bd5b10d37357378f7c8e629d97c1eafac1a916cd2ff50f25136a137da93a' 
  AND token = 'N6tz6HxV/BB3WI8X+Id0wPAsc1F9w48dVEvj82k8+mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}