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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8287079e4170bd88a7104e7d64ddfed17982f47bd4d514a7150a585c7437866' 
  AND token = 'j+o+/kIlriVWFSXfiRxoeH6rIeoEnNZwhr3aUQsLWb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}