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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88dfb421c6732827e58cd4ce45cf7ac2ad2c2f1cb787ba96da84e706a85887ff' 
  AND token = 'zOp9WVsX6SEl0R5Hoi208Ea5SeVHC+6UtGGLlBN+Yc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}