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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6154d65a098124ca2703fb66fdc4df83c47ce2961e8e82b561d9ff942c00341d' 
  AND token = 'v4JqQygFX+pF8F4qRkUBNDMtsQyeDRtv+cGJGD37Sxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}