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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645aef2b42613d2af6f16956b7fd545ec32b659f7834ef8ab4cb0aa191267f4b' 
  AND token = 'uf5U5k0yCJO31Dwh0poqsJNhe5fBnOUaSUeqYtEA5Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}